Interestingly, Weber-Lassalle et al. reported a much stronger association (OR = 5.4; p < 0.00001; n = 4469) in BC patients with a family history of BC and an even higher risk (OR = 12.0; p < 0.00001; n = 782) for BC patients diagnosed under 40 years of age, suggesting that BARD1 might be a risk gene for early-onset familial BC [15]. The gene discussed is BARD1; the disease is breast cancer.