In lupus nephritis, a severe and frequently-occurring secondary kidney-specific inflammation following SLE, oral dihydroartemisinin (5–125 mg/kg/d) was found to suppress serum levels of anti-dsDNA antibody and TNF-α and abrogate renal pathology in mice via blockade of NF-κB p65 subunit nuclear translocation [204]. Here, RELA is linked to lupus nephritis.