SOD1 and type 2 diabetes mellitus: When subjects within each study population were stratified in HPR+ and HPR- according to their response to CEPI PFA-100 (Table 4), we found that HPR+ differed from HPR- for—(i) SOD activity (p = 0.002), soluble p-selectin (sP-selectin) (p = 0.001), sRAGE (p = 0.004), and 11-dhTXB2 (p = 0.035) levels in HC patients; (ii) SOD activity (p = 0.0001), 8-iso-PGF2α (p < 0.0001), sCD40L (p = 0.003), and 11-dhTXB2 (p = 0.042) in T2DM patients.