NFE2L2 and neuroblastoma: Similarly, the expression levels of MFN1, MFN2, OPA1 and NRF2 are reduced, but those of DRP1 and FIS1 are increased in mAPP neuroblastoma cells (N2a cells), accompanied by reduced protein levels of mitochondrial biogenesis factors (PGC1α, NRF1, Nrf2, and TFAM).