In the recessive test model, the CC and CT/TT genotype frequencies of GPX4 (rs713041) were 33 (36.7%), and 57 (63.3%) in endometriosis cases, and 22 (16.9%), and 108 (83.1%) in the control group, respectively (p = 0.001, X2 test). This evidence concerns the gene GPX4 and endometriosis.