PLAGL1 and cervical cancer: Moreover, low dosage (1 μg) of mZac1.HA have more significant impact on EMT markers comparing with high dosage (3 μg) in SiHa and Caski (Fig. 7B), suggesting that EMT may optimally induced by moderate level of Zac1 expression, which is corresponds to previous observation comparing normal and cervical cancer with high Zac1 expression (Fig. 4A).