Notably, some of the nine differential proteins (3HAO, ASAH1, CHMP5, FPRP, IBP3, MERTK, MUC18, NRP1, and PRIO) in tumor-forming rats have already been reported to be associated with lung cancer biomarkers/pathology/mechanisms or ovarian cancer metastasis. Here, IGFBP3 is linked to neoplasm.