CXCL8 and neoplasm: Upon comparing the functional enrichment analysis results between the tumor-forming and non-tumor-forming rats, we found that some of the functional terms were enriched only in tumor-forming rats, such as the cell migration and transepithelial transport terms (Fig. 4A1 and 2, respectively); the coagulation system, IL-8 signaling, and TGF-β signaling terms (Fig. 4B1, 5, and 10, respectively); and the phosphorylation of L-amino acid, size of tumor, growth of tumor, and migration of tumor cell line terms (Fig. 4C1, 2, 3, and 4, respectively).