For the latter, we found a significant enrichment in the inactive (Dyrk2 KR, p-value = 2.05e−04) as well as in the putatively still active Dyrk2 PL mutant (p-value = 2.56e−06), consistent with the reported role of Dyrk2 in cancer metastasis9,33,34. This evidence concerns the gene DYRK2 and cancer.