DIAPH1 and autosomal dominant nonsyndromic hearing loss 1: To further investigate which cells in the cochlea and which sites within the cells relate to constitutively active DIA1 mutant function and pathogenesis in DFNA1 patients, we generated AcGFP-DIA1(R1213X) knock-in (KI) (DIA1KI) mice (Fig. 4a, details about hearing function in this mouse line is being preparation for another publication).