IL13 and acute myeloid leukemia: Interestingly, although it neither reached statistical significance after multiple testing correction, we also found a negative correlation between the IL13rs1295686A allele and levels of IL1Ra after stimulation of PBMCs with LPS (P = 0.002; Fig. 1c), which suggested that the IL13 locus might play a role in the pathogenesis of AML likely through the modulation of IL1Ra-mediated immune responses.