HSD17B4 and neoplasm: Statistical analyses of quantified images indicated that the differences in total HSD17B4 protein levels (P < 0.001), in K669-acetylated HSD17B4 (P < 0.001), and in the ratio of K669-acetylated HSD17B4 versus total HSD17B4 proteins (P < 0.001) between tumor and normal tissues are all significant (Figure 8B).