Previous studies have revealed that KLF7 can promote polyamine biosynthesis and glioma development by activating argininosuccinate lyase [21], and meanwhile, KLF7 can be modulated by Linc00669/miR-193a axis and it can advance non-small cell lung cancer [20], suggesting that KLF7 is an oncogene. This evidence concerns the gene KLF7 and central nervous system cancer.