Currently, wet age-related macular degeneration (wAMD) is the only form of AMD that can be treated with vascular endothelial growth factor inhibitors (anti-VEGF), which has been shown to be effective in maintaining vision in more than 90% of patients and improving it in 25 ~ 40% of patients [5]. The gene discussed is VEGFA; the disease is age-related macular degeneration.