To gain insights into the precise role of the DANCR/KAT6A complex in mediating the function of TRIM24 in colorectal carcinoma, we inhibited the expression of DANCR or KAT6A in both SW620 and HT29 cells, and found that both mRNA and protein expression of YAP were inhibited (Figure 4A and B). The gene discussed is KAT6A; the disease is colorectal carcinoma.