Upon comparing the clinical and demographic data in EOPD patients, with or without Parkin gene variants, those with Parkin gene variants had a younger age at onset (27.13 ± 8.10 vs. 39.93 ± 4.15), longer diagnostic delay (10.63 ± 5.71 vs. 1.83 ± 1.10), slower disease progression (14.13 ± 5.54 vs. 3.93 ± 2.12), lower grades of H‐Y(3.13 ± 0.83 vs. 2.20 ± 0.86), and higher frequency of hyperreflexia (75.0% vs. 20.0%) (all p < .05) (Table 2). Here, PRKN is linked to Hyperreflexia.