In line with our previous findings, IL‐18, a keratinocyte‐derived chemokine that is related to contact sensitizer potency in reconstructed human skin epidermis,21 and CXCL12, a chemoattractant that is pivotal in mediating LCs migration during skin sensitization,48 were found to be higher in RHS than in RHG regardless of the presence of S. mitis. Here, CXCL12 is linked to skin sensitization.