Zhang et al. demonstrated augmented CXCR4 expression in the infarct zone as early as 24 hours after acute myocardial infarction by immunofluorescent CXCR4 staining in the infarct border zone13 with increased levels up to day 7 which corroborates our CXCR4 expression kinetics. This evidence concerns the gene CXCR4 and acute myocardial infarction.