MEFV and familial Mediterranean fever: According to MEFV gene mutations analysis, more than 300 mutations have been reported20; the five most frequent mutations in the Middle East are M694V, M694I, V26A, E148Q, and M680I mutations.7 Our results show that the most frequently reported mutations were E148Q, V726A, M680I, M694V, and M694I and were detected in 25.26%, 20%, 20%, 17.89%, and 7.37% of FMF patients, respectively.