CXCL8 and coronary artery disorder: Prior research on patients and cell culture models [8, 9] has shown that IL-8 is involved in the pathogenesis of cardiovascular disorders including CHD [10], MI [11], strokes, [12], and other diseases such as ankylosing spondylitis [13], emphysema [14], periodontitis [15], and systemic lupus erythematosus [16].