Compared to the PBS-injected group (without S. agalactiae infection), the bacterial infection markedly induced the transcriptional levels of IL-1β (head kidney: 50.7-fold at 3 hpi; spleen: 5.9-fold at 3 hpi; liver: 26.4-fold at 3 hpi), TNFα (head kidney: 2.4-fold at 3 hpi; spleen: 5.5-fold at 96 hpi; liver: 9.1-fold at 3 hpi), and IL-10 (head kidney: 10.5-fold at 3 hpi; spleen: 23.4-fold at 12 hpi; liver: 16.3-fold at 3 hpi) in S. agalactiae-treated group. The gene discussed is IL1B; the disease is bacterial infectious disease.