IL6 and COVID-19: Moreover, inflammatory cytokines, such as TNF-α, IL-1β, and IL-6 induce the synthesis of acute phase proteins by the liver, including fibrinogen (Mackiewicz et al., 1991), thereby producing a pro-coagulant state, at least in the venous circulation, and may also contribute to the increased arrhythmic risk observed in COVID-19 patients (Lazzerini et al., 2020).