Therefore, the simultaneous targeting of c-Myc and HDAC6 using the bromodomain and extra terminal protein family members inhibitor JQ1 and the HDAC6 inhibitor ricolinostat (ACY-1215) can effectively induce apoptosis of MM tumor cells in xenograft mice and inhibit proliferation (Carew et al., 2019) (Figure 1B). Here, HDAC6 is linked to Miyoshi myopathy.