The patients in the SAb−/GAg − group showed less deteriorated disease markers than in the SAb+/GAg+ group, including albumin levels, 24-h urinary protein, glomerular sclerosis ratio, arteriosclerosis, IgG deposition, C1q deposition, Ehrenreich and Churg’s stage, and a requirement for treatment. This evidence concerns the gene SH3BP5 and Glomerular sclerosis.