CAT and diffuse large B-cell lymphoma: In diffuse large B-cell lymphoma (DLBCL) patients who were refractory to another HDAC inhibitor, panobinostat, the expression of peroxisome gene transcripts, including FAR1, FAR2, and CAT, was also increased, supporting the idea that peroxisome upregulation is associated with resistance against ROS-mediated cancer cell death [85].