Another mechanism involved in the regulation of host responses to fungal infection via the extracellular ATP released by C. albicans is associated with the candidalysin-dependent triggering of the host innate immunity through processes related to the activation of epidermal growth factor receptor (EGFR) in the oral epithelial cells, followed by MAPK signaling and the production of inflammatory cytokines [164]. The gene discussed is EGFR; the disease is fungal infectious disease.