More recent studies demonstrated the anti-proliferative potential of C/EBPs through their repression of a cluster of microRNAs that induce the expression of the tumor suppressor phosphatase PH domain and leucine rich repeat protein phosphatase 2 (PHLPP2) in acute myeloid leukemia (AML) cells [22]. The gene discussed is PHLPP2; the disease is acute myeloid leukemia.