The cellular genes containing the motif encode collagen type IValpha-3-binding protein (COL4a3BP), an ER transmembrane transporter of ceramide; deleted in malignant brain tumors 1 protein (DMBT1), a candidate tumor suppressor; melanoma-associated antigen C3 (MAGEC3), a tumor antigen; ubiquitin-protein ligase E3A (UBE3A), a ubiquitin ligase of the proteasomal pathway; cell division cycle 7-related protein kinase (CDC7), a cell cycle regulating kinase; and Rho associated coiled-coil-containing protein kinase 1 pseudogene 1 (ROCK1P1), a pseudogene. This evidence concerns the gene UBE3A and neoplasm.