In the mixed-effects Cox model, after adjusting for age, sex, and coexisting comorbidities, the significant associations between increased cardiac injury biomarkers and a higher risk of COVID-19 mortality were still maintained with adjusted HR of 4.42 ([95% CI, 2.74–7.13] P<0.001) for hs-cTnI, 2.98 ([95% CI, 1.94–4.59] P<0.001) for CK-MB, 5.46 ([95% CI, 2.55–11.73] P<0.001) for (NT-pro)BNP, 1.57 ([95% CI, 1.00–2.45] P=0.048) for CK, and 2.92 ([95% CI, 1.76–4.85] P<0.001) for MYO. Here, NPPB is linked to COVID-19.