AXL and osteosarcoma: Similarly, the average number of 143B cells passed through the matrigel‐coated Boyden chamber microporous membrane increased from 74 to 183, while that of HOS increased from 11 to 175 (Figure 1I, Fig. S4; P = .000).These results indicated that the exosomes from osteosarcoma cells with high AXL expression could increase migration and invasion of osteosarcoma cells with low AXL in vitro.