Furthermore, linc00852 was especially highly expressed in the poorly differentiated osteosarcoma cell lines as 143B and HOS, which were 3.4 and 2.5 times higher than that in NIH3T3 cells, separately(Figure 2E 143B; P = .000, HOS; P = .000). The gene discussed is LINC00852; the disease is osteosarcoma.