These molecules show potential in cancertherapy, especially considering some recent findings where the expressionlevels of miRNA-processing machinery components (i.e., Drosha andDicer) were decreased in some cancers, which was often associatedwith a poor clinical outcome.31,32 In addition, therehave been reports showing that miRNA biogenesis machinery componentsexhibit normal expression in cancer, but with a widespread suppressionof miRNAs.16 Here, DROSHA is linked to cancer.