PTEN and neoplasm: Given the frequency of the disease in the population (Cancer Research UK statistics 2015 https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/breast-cancer) and the frequency of PTEN alterations in this type of tumor (Cancer Genome Atlas Network, 2012), we can estimate that up to 15,000 patients may be diagnosed every year in the United States and 22,000 per year in the European Union with a PTEN‐deficient triple‐negative invasive breast cancer.