After stably knockdown cell line establishment, we performed immunoblotting to validate the PGRMC1 expression levels in OC3 and OC3‐I5 cells transfected with shPGRMC1 or shLacZ (Figure 6A), and the invasion ability of cells was also investigated before tumour implantation in mice (Figure 6B). Here, PGRMC1 is linked to neoplasm.