However, Wang et al. suggested the only nonsignificant relationship of Lgr5 alone with OS and Lgr5 has been in addition described in Jiang et al.’s study, different from our results as prognostic marker for better clinical outcome in CRC patients (Wang et al. 2018a; Zheng et al. 2018). This evidence concerns the gene LGR5 and colorectal carcinoma.