In case of CD44, this protein is a cell surface glycoprotein expressed commonly on lymphocytes, monocytes, and granulocytes and it has been interestingly suggested, that the absence of stromal CD44 expression was connected with an increased death rate of patients with CRC (Furuta et al. 1996, 1998; Cairns et al. 2001). The gene discussed is CD44; the disease is colorectal carcinoma.