MAPK1 and psoriasis: Furthermore, several other proteins, including IL-1α/β, eNOS, iNOS, PPAR-γ, MAPK2, JAK1/2/3, and STAT3, were identified as possible novel therapeutic targets, which are overexpressed in psoriasis patients (Mittal et al., 2009; Rácz and Prens, 2009).