The focal adhesion kinase PTK2, a gene in the core of the Focal Adhesion pathway, and its central activator fibronectin 1 (FN1), as well as upstream integrin subunits ITGB1, ITGB3, and ITGA5, paxillin (PXN), and thrombospondin 1 (THBS1) represented hub nodes next to the common cancer associates VEGFA and EGFR, and all these genes are part of the Focal Adhesion pathway. This evidence concerns the gene THBS1 and cancer.