In a similar population, a radiomics predictive model was constructed based on computer tomography (CT) images which was able to predict the immunohistochemical characteristics of suspected thyroid nodules [cytokeratin 19 (AUC 0.87, sensitivity 93%, and specificity 73%), galectin 3 (AUC 0.85, sensitivity 87%, and specificity 76%), and thyroperoxidase (AUC 0.84, sensitivity 86%, and specificity 75%)] (65). This evidence concerns the gene LGALS3 and thyroid nodule.