The inhibitory role of miR-19a in septic AKI was further evidenced by the biochemical detection showing that CLP-treated mice displayed increased levels of cleaved caspase-3 (Figure 4(e)), serum creatinine (Scr) (P < 0.0001, Figure 4(f)), blood urea nitrogen (BUN) (P = 0.0033, Figure 4(g)), and lactate (P < 0.001, Figure 4(h)) in contrast to their littermates, the phenotypes that could be counteracted by miR-19a delivery. This evidence concerns the gene CASP3 and acute kidney injury.