Blood purification could nonspecifically remove the inflammatory mediators with moderate molecular weights such as tumour necrosis factor-α, interleukin (IL)-1β, IL-6, and IL-8, which can activate and lead to progressively “waterfall-like” chain reaction playing an important role in the pathogenesis of SIRS [26, 27]. Here, CXCL8 is linked to systemic inflammatory response syndrome.