Renal agenesis occurred in 8 of the 20 patients, which may be caused by an ANOS1 deletion (Martul et al., 1995; Krishnamurthy et al., 2007; Macarov et al., 2007; Trevisson et al., 2015; Xu et al., 2015; Nagai et al., 2017). The gene discussed is ANOS1; the disease is renal agenesis.