We found collectively among SP-A variants several genes such as AKT1, BTK, CCL9, PPARG, and RELA to exhibit higher expression in females, whereas, CFLAR, C1QC, LSP1, CKAP2, KAT2B, TACC2, and RCC2 exhibited higher expression in males after infection (Figure 7). The gene discussed is AKT1; the disease is infection.