SAMHD1 and infection: However, in response to infection, male mice exhibited higher expression levels of CXCL2 (KO, 1A3, and 6A2), SAMHD1 (1A0, 1A3), RSAD2, STAT1, and STAT3 (1A0), MYD88 and PSMB8 (1A3), BCL3, BCL10, CCRL2, IFITM2, RTP4, and ZFP36L1 (6A2), compared to females (Figure 6).