PDGFRA and gastrointestinal stromal tumor: In particular, it has been found that PDGFRA mutant GIST displays more immune cells with increased cytolytic activity; express higher levels of many chemokines, such as CXCL14; exhibit more diverse driver-derived neoepitope-HLA binding proteins; and have additional immune features of high PD-1 and PD-L1 expressing tumors.