PDGFRA and gastrointestinal stromal tumor: In this intriguing scenario, the aim of this study was to specifically evaluate the immune-profile of D842V mutant GIST compared to non-D842V mutant GIST, in order to better understand if the prominent immune features belong to all PDGFRA mutant GIST or if it is a specific peculiar fingerprint of D842V mutants, widely recognized as the drug-orphan subset of GIST.