MOG and neuromyelitis optica: Interestingly, for MOG-antibody-associated disease, besides NMO phenotype, optic neuritis, and myelitis, some of these MOG-antibody-positive cases also have clinical phenotypes beyond the current NMOSD spectrum, such as ADEM/MDEM-like presentation (71), cerebral cortical encephalitis (12), and cranial nerve involvement (14).