AKR1B1 and gout: We found that 17 formula targets overlapped with gouty arthritis related-genes, including STAT3, FN1, APOB, AIFM1, PTGER1, ALB, TNF, VEGFA, LPL, PPARa, SREBF2, CASP8, JUN, FOS, AR, TTR, and AKR1B1 (Figure S3).