Nine shared signaling pathways (including AMPK, FoxO, ErbB, HIF-1, Jak-STAT, PI3K-Akt, Rap1, Ras, T cell receptor), 30 shared disease pathways (7 tumor related pathways, 13 infectious disease related pathways, 6 immune system disease related pathways, 4 endocrine disease pathways). The gene discussed is EGFR; the disease is endocrine system disorder.