MAPT and supranuclear palsy, progressive, 1: However, tau seeding and propagation in neurons, astrocytes and oligodendrocytes was observed following inoculation of paired helical filament (PHF)-enriched fractions from CBD and PSP; deposits in astrocytes comparable to astrocytic plaques were reported following inoculation of CBD, and doubtful tufted astrocytes following inoculation of PSP homogenates (Narasimhan et al., 2017).