The MetaCore pathway analysis suggested that “signal transduction: angiotensin II/angiotensin II receptor type 1 (AGTR1) signaling via Ras homolog family member A (RhoA) and c-Jun N-terminal kinase (JNK)” had a high correlation with breast cancers exhibiting PODXL2 expression (Supplementary Figure 1). This evidence concerns the gene RHOA and breast cancer.