TRIM33 and laryngotracheoesophageal cleft: In our pilot study, we demonstrated aberrantly high expression of TIF1γ protein existed in cancer tissues other than matched paracancerous tissues of patients with lung cancer (LC) at early stage by immunohistochemistry (IHC) staining, which indicated that serum autoantibodies against TIF1γ might be promising approach for the early diagnosis of patients with LC.