The AUC of anti-TIF1γ-IgA for the patients with early LC was 0.704, with 28.20% sensitivity at 95.93% specificity, and the AUC of anti-TIF1γ-IgG for the patients with early LC was 0.622, with 18.54% sensitivity at 94.25% specificity. The gene discussed is CD79A; the disease is laryngotracheoesophageal cleft.