FKBP1B and cyclic hematopoiesis: Furthermore, FKBP12.6−/− mice developed significantly higher RVSP relative to WT mice after CH (42 ± 1.4 mmHg versus 36.3 ± 1.8 mmHg, P < 0.05), while there was no difference between FKBP12.6−/− and WT mice under normoxic conditions (19 ± 0.7 mmHg versus 18 ± 1.0 mmHg, P > 0.05, Fig. 4e).