IL37 and enthesitis: Figure 2B displays a heatmap of the cytokine profiles in the individual patients. The dendogram shows that IL-23 clusters away from all other cytokines and separates best responders and non-responders to MTX monotherapy at baseline. Clinically, the definite non-responders had at baseline a significantly higher TJC, higher pain VAS, higher global VAS, higher HAQ score, but lower enthesitis score (table 3).