However, in this study, the mature oocytes with FSH and hCG priming were capable of being fertilized (75, 77.5%) and developed to blastocyst embryos (57.1, 62.5%) in PCOS and non-PCOS groups, respectively, as shown in Table 2, and even the size of these follicles was less than the size in standard IVF protocols. The gene discussed is BRD2; the disease is polycystic ovary syndrome.