BRD4 and small cell lung carcinoma: In addition, a number of super enhancer (SE)-associated transcripts were identified in NCI-H1963 SCLC cells, which is based on the ranking of H3K27Ac ChIP-seq signals (Fig. 4e) or BRD4 ChIP-seq signals (Additional file 2: Figure S5F), and a number of ASXL3 downstream targets were associated with SEs, such as TCF4, SMARCA2, COL9A2, and KLHL14 (Fig. 4e and f).