As expected, ASXL3 protein was reduced by dBET6 treatment in both dose- and time-dependent manners (Fig. 5g and h) and is also shown to be effective in other SCLC cell lines, such as NCI-H69, NCI-H1982, and NCI-H748 (Additional file 2: Figure S6C). The gene discussed is ASXL3; the disease is small cell lung carcinoma.